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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4A All Species: 23.94
Human Site: T1149 Identified Species: 35.11
UniProt: O95239 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95239 NP_036442.3 1232 139881 T1149 L E D P T E V T P G L S F F N
Chimpanzee Pan troglodytes XP_518055 1227 139177 T1144 L E D P T E V T P G L S F F N
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 T1151 L E D P T E V T P G L S F F N
Dog Lupus familis XP_549061 1234 139874 T1151 L E D P T E V T P G L S F F N
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 T1149 L E D P T E V T S G L S F F H
Rat Rattus norvegicus Q7M6Z5 1394 158861 P1304 E D G P D S L P V C G S L A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 L1141 D S E G S F K L E D L R D V T
Frog Xenopus laevis Q91784 1226 138905 T1145 K I D Y P D V T A G G S F F T
Zebra Danio Brachydanio rerio Q58G59 1363 154819 R1274 Q K S R E E M R E P V N A P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 S703 D D I D I V D S H T N S L R S
Honey Bee Apis mellifera XP_395595 1064 123475 C983 T T C A T R I C K C R K R K A
Nematode Worm Caenorhab. elegans P46873 699 78760 L618 R S N F D D K L R E R L A K S
Sea Urchin Strong. purpuratus P46872 699 78679 K618 D I G E W Q L K C V A Y T G N
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 T965 A Q K Q L K Y T P G I A N G S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199593 1035 116715 P954 A N G K V R G P A A F L D T N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 N847 Q E K M A Q A N H K F E V Q L
Conservation
Percent
Protein Identity: 100 93.1 96.4 94.8 N.A. 87 27 N.A. N.A. 74.5 68.5 25.8 N.A. 26.9 36.8 27.1 27.3
Protein Similarity: 100 95.6 97.2 97 N.A. 92.7 47.6 N.A. N.A. 85.9 82.1 45.1 N.A. 41.4 56.3 38.4 39.3
P-Site Identity: 100 100 100 100 N.A. 86.6 13.3 N.A. N.A. 6.6 46.6 6.6 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 26.6 N.A. N.A. 20 53.3 33.3 N.A. 26.6 13.3 20 20
Percent
Protein Identity: 33.2 N.A. N.A. 32.7 N.A. 26.7
Protein Similarity: 51 N.A. N.A. 51 N.A. 44.5
P-Site Identity: 20 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 53.3 N.A. N.A. 6.6 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 7 7 0 7 0 13 7 7 7 13 7 7 % A
% Cys: 0 0 7 0 0 0 0 7 7 13 0 0 0 0 0 % C
% Asp: 19 13 38 7 13 13 7 0 0 7 0 0 13 0 0 % D
% Glu: 7 38 7 7 7 38 0 0 13 7 0 7 0 0 0 % E
% Phe: 0 0 0 7 0 7 0 0 0 0 13 0 38 38 0 % F
% Gly: 0 0 19 7 0 0 7 0 0 44 13 0 0 13 0 % G
% His: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 7 % H
% Ile: 0 13 7 0 7 0 7 0 0 0 7 0 0 0 0 % I
% Lys: 7 7 13 7 0 7 13 7 7 7 0 7 0 13 0 % K
% Leu: 32 0 0 0 7 0 13 13 0 0 38 13 13 0 13 % L
% Met: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 0 7 0 0 7 7 7 0 38 % N
% Pro: 0 0 0 38 7 0 0 13 32 7 0 0 0 7 7 % P
% Gln: 13 7 0 7 0 13 0 0 0 0 0 0 0 7 0 % Q
% Arg: 7 0 0 7 0 13 0 7 7 0 13 7 7 7 0 % R
% Ser: 0 13 7 0 7 7 0 7 7 0 0 50 0 0 19 % S
% Thr: 7 7 0 0 38 0 0 44 0 7 0 0 7 7 13 % T
% Val: 0 0 0 0 7 7 38 0 7 7 7 0 7 7 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 7 0 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _